Palazzo dei Priori is a historic building located in the heart of Perugia, a city in the central region of Umbria, Italy. Built in the 13th century, it is one of the most significant examples of Gothic civic architecture in Italy. The palace was originally the seat of the city's government, and today houses the National Gallery of Umbria, which features works of art from the Middle Ages to the 19th century.

The building has an impressive facade with a central tower, a series of arches, and numerous balconies. The interior is equally impressive, with a large atrium and a grand staircase leading to the upper floors. The palace is also home to a number of important civic institutions, including the town council and the court of justice.

One of the most significant works of art housed within the Palazzo dei Priori is the "Madonna and Child Enthroned with Four Angels," a painting by the 14th-century artist Duccio di Buoninsegna. The National Gallery of Umbria also contains other important works of art by artists such as Perugino, Pinturicchio, and Fra Angelico.

Palazzo dei Priori is open to the public for tours and exhibitions, and is a popular destination for visitors to Perugia. The building is located in the city's historic center, near the famous Fontana Maggiore and the Cathedral of San Lorenzo.