The Musée des Confluences is a science and anthropology museum located in Lyon, France. The museum was opened in 2014 and is situated at the confluence of the Rhône and Saône rivers, where the name of the museum comes from. The building was designed by the Austrian architecture firm Coop Himmelb(l)au and is recognized for its avant-garde and futuristic design.

The museum's collection features exhibits on natural sciences, anthropology, and societal issues, with a particular emphasis on the interaction between humans and the environment. The exhibits include over 2 million objects and specimens from around the world, ranging from prehistoric fossils to contemporary art. The museum also features interactive exhibits and multimedia installations that provide visitors with a hands-on and immersive experience.

The Musée des Confluences has received several awards and has been recognized for its innovative design and exhibits. It attracts over 300,000 visitors annually and is considered one of the most important cultural institutions in Lyon.