The Duomo di Catania, also known as the Cathedral of Saint Agatha, is a Baroque-style cathedral located in the historic center of Catania, a city in the region of Sicily, Italy. The cathedral is dedicated to Saint Agatha, the patron saint of Catania, who was martyred in the 3rd century AD.

The original structure of the cathedral was built in the 11th century and underwent several renovations and reconstructions throughout the centuries due to damages caused by earthquakes and volcanic eruptions. The current facade of the cathedral was completed in the 18th century, designed by the architect Giovanni Battista Vaccarini in Baroque style.

The interior of the cathedral features beautiful Baroque decorations and paintings, including a large silver bust of Saint Agatha, which contains her relics. The cathedral also houses several important works of art, such as a painting by Caravaggio's disciple, Luigi Vanvitelli.

One of the most remarkable features of the cathedral is its bell tower, which stands at over 70 meters tall and offers panoramic views of the city and the surrounding areas.

The Duomo di Catania is a significant religious and cultural landmark in the city and attracts numerous visitors and pilgrims each year. It is also part of the UNESCO World Heritage Site known as the "Late Baroque Towns of the Val di Noto," which includes several other cities and towns in southeastern Sicily that feature unique examples of Baroque architecture and town planning.